I have to agree that there are too many variables to give specific advice, but I can relate what my wife, a CPA, did when we got married and moved from Connecticut where she had a tax practice. She did, and still does, work from home with a separate home-office dedicated to the business, which saves tons of money on rent, etc. That isn't your case.
But, to build the business, we went to the library (now you would just go online) and looked up recent home sales, and we sent the new homeowner a welcome letter and a refrigerator magnet advertising her tax and accounting service. That worked amazingly well, because the new homeowners would probably be looking for an accountant, and the refrigerator magnet served as a reminder when tax season came around. Also, unlike bulk advertising, we were able to target people new to the area, where they lived since people prefer services near where they live, and probable income based on price of the home.
If you are looking for business clients, you can do a similar search with your local business licensing agency.
We had a couple hundred business card size refrigerator magnets printed up by mail order; now you would just go to Staples or online. The magnet size does matter, too small and people will just throw it away, too big and people would be annoyed by how imposing it appears. We wanted something just the right size so potential clients would keep it to post stuff, kid's art, school lunch schedule, notes, etc. on their refrigerator.
Modern electronic advertising, so long as you can target your desired demographic, would probably be a good idea. Our practice start-up predates this, but it wold probably be a good approach. Here, I would suggest Angie's List, Google AdWords and Yelp.
To become profitable you need clients, and the right size business. While it didn't apply to us, since we have the home-office based practice, friends who started up who were profitable quickly began in a small office and then moved to larger space when they outgrew their office. So long as you don't move too far, the clients will follow. That may guide you in shopping for rental space.